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Pharyngitis

Epidemiology

-         Sore throat

-         Inflammation of the pharynx, and surrounding lymphoid tissue that my be viral or bacterial origin

-         Virus appear to the cause of majority of episode

-         B-hemolytic streptococci being the most prevalent microorganism.

Signs and symptoms

-         Sore throat associated with dysphagia and fever

-         Hyperemia of pharynx and hypertrophied tonsil

-         Gas: B-hemolytic Streptococcus

o       Presence of a tonsillar exudates

o       Swollen and tender cervical node

o       Lack of cough

o       History of fever greater than 38

Pharmacological therapy

-         Penicillin

o       Drug of choice

o       250 mg twice daily orally for 10 days

o       injectable forms of penicillin (IM) increases the risk of allergic reaction and painful but favors compliance

-         ampicillin and Amoxicillin offer no advantage over penicillin

-         penicillin-allergic patient

o       erythromycin estolate 20-40 mg/kg/d for 10 days

-         macrolide

o       azithromycin

o       2nd line of agent